A dentist appeared in court on Monday following the mysterious disappearance of his lawyer wife which is now being treated as a murder investigation.
Dr Majid Mustafa, 47, has been charged with conspiring to administer a noxious substance to Renata Antczak, 49, who has been missing for eight weeks.
Hull Crown Court heard Mustafa also faces another charge of conspiring to cause a man called Dariusz Kleinert grievous bodily harm with intent.
Dr Majid Mustafa (left) is charged with conspiring to poison his wife Renata Antczak (right)
Humberside Police launched a murder investigation following her disappearance last Friday.
Mustafa appeared an hour before Robert Lipinski, 45, who is jointly charged with administering a noxious substance to Renata.
Lipinski is further charged with conspiracy to administer a noxious substance to Anna Lipinski.
They both spoke to only confirm names and addresses after appearing in the dock.
Ms Antczak was last seen eight weeks ago near her home in Hull after she had dropped her daughter off at school
Mustafa, who donned a blue shirt and trousers with a brown belt, sat quietly through the hearing and showed little emotion.
Lipinski addressed the court through a Polish interpreter.
Speaking to the two defendants during the six minute hearing, Recorder of Hull Judge Jeremy Richardson, QC, said: ‘You are remanded in custody.
Humberside Police have launched a murder investigation int the disappearance
‘The defence statement is a crucial document and it must be served by the due date.
‘You are remanded in custody – you can now go.’
Both Mustafa and Lipinski will next appear at Hull Crown Court later in the year for a case management hearing in September.
Renata was last seen near hear home after dropping her daughter off at school.
Mustafa has been remanded in custody until his trial